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DNA strand

FDA approves trial to advance pioneering treatment for Hereditary Spastic Paraplegia (HSP)

The US Food and Drug Administation (FDA) has approved BlackfinBio Limited’s Phase 1/2 clinical trial for its novel adeno-associated virus (AAV) gene therapy targeting Hereditary Spastic Paraplegia (HSP) Type 47 (SPG47).
DNA strands

Sheffield spinout takes major step towards advancing pioneering treatments for Hereditary Spastic Paraplegia (HSP)

BlackfinBio Limited is a spinout company from the º£½ÇÉçÇø of Sheffield set to pioneer novel therapies for rare genetic neurological diseases.

Image of motor neurones

Groundbreaking EXPERTS-ALS study for MND treatments

The EXPErimental medicine Route To Success in ALS (EXPERTS-ALS) project aims to rapidly screen potential drugs for evidence that they can slow down damage to the nervous system occurring in people with motor neuron disease
Professor Mimoun Azzouz holding a petri dish

Comment: Turning the biggest disappointment of a career into a new era for UK gene therapy manufacturing

Professor Mimoun Azzouz discusses career challenges before opening the Gene Therapy Innovation and Manufacturing Centre (GTIMC) at the º£½ÇÉçÇø of Sheffield.
Chronic nerve pain

The link between cell ‘dark matter’ and chronic nerve pain

Our researchers have found a link between neuropathic pain and ‘dark matter’ in cells, which could lead to new treatments for patients with chronic nerve pain.
SITraN Building

Scientists awarded funding for pioneering dementia research

The new research projects will explore the processes behind Alzheimer’s and dementia which could lead to new approaches in how they are treated.
Test tubes

A new treatment for Parkinson’s disease

A Sheffield academic has been awarded funding to develop a new treatment for Parkinson’s disease, that could potentially slow, or even stop its progression.

MRC Festival of Medical Research 2019

On 15 and 16 June 2019, scientists from the Hearing Research Group at the º£½ÇÉçÇø of Sheffield’s Neuroscience Institute shared their latest research on hearing and hearing loss.
Neuroscience fotm mouth

Repairing nerves with 3D printing

Our researchers are using a unique library of human tissue – and biocompatible 3D printed materials – to improve patient treatment and quality of life.