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Professor Dame Pamela Shaw
Professor Dame Pamela Shaw

World-renowned MND researcher and clinician says making research easier to understand, and showing why it matters, is vital

One of the world鈥檚 leading scientists on motor neurone disease (MND) and other neurological diseases says making complex research more accessible and understandable is vital to show progress is being made at developing treatments for the conditions.
DNA strand

FDA approves trial to advance pioneering treatment for Hereditary Spastic Paraplegia (HSP)

The US Food and Drug Administation (FDA) has approved BlackfinBio Limited鈥檚 Phase 1/2 clinical trial for its novel adeno-associated virus (AAV) gene therapy targeting Hereditary Spastic Paraplegia (HSP) Type 47 (SPG47).
DNA strands

Sheffield spinout takes major step towards advancing pioneering treatments for Hereditary Spastic Paraplegia (HSP)

BlackfinBio Limited is a spinout company from the 海角社区 of Sheffield set to pioneer novel therapies for rare genetic neurological diseases.

Image of motor neurones

Groundbreaking EXPERTS-ALS study for MND treatments

The EXPErimental medicine Route To Success in ALS (EXPERTS-ALS) project aims to rapidly screen potential drugs for evidence that they can slow down damage to the nervous system occurring in people with motor neuron disease
Neuroscience fotm mouth

Repairing nerves with 3D printing

Our researchers are using a unique library of human tissue 鈥� and biocompatible 3D printed materials 鈥� to improve patient treatment and quality of life.
Head up collar

The Goldilocks collar

Everyone values their independence. But motor neurone disease takes it from over 2,000 of us a year in the UK. Professor Chris McDermott and his team wanted to transform the lives of their patients by giving them some independence back.

Neurons

New gene variation which causes MND discovered in novel biological pathway

Scientists have discovered a new gene variation that causes motor neurone disease (MND) in a novel biological pathway that until now hasn鈥檛 been linked with neurodegeneration.
Nerve cells

Scientists identify new disrupted pathway in MND

Researchers at the 海角社区 of Sheffield have identified a new pathway that is disrupted in motor neurone disease (MND), a discovery which could pave the way for new treatments.
Parkinson's disease: nerve cells - illustration

Liver drug trialled in Parkinson鈥檚 patients as novel treatment approach

A drug which has been used to treat liver disease for over 30 years is being trialled in patients with Parkinson鈥檚 Disease to determine its safety and tolerability in Parkinson鈥檚, but also to assess its potential to slow down disease progression for the first time.